4-Hydroxynonenal-d3 [CAS 148706-06-3]
4-Hydroxynonenal-d3 [CAS 148706-06-3]
SKU:QM-0058776
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Product Details
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Description
4-Hydroxynonenal-d3 is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α, β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2) . 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].
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CAS Number
[148706-06-3]
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Molecular Formula
C9H13D3O2
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Molecular Weight
159.24
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Smiles
O=C/C=C/C(O)CCCCC([2H])([2H])[2H]
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Target
Aldehyde Dehydrogenase (ALDH) ; Endogenous Metabolite; Isotope-Labeled Compounds
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Isoform
ALDH2
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Concentration
3.14 mM * 100 μL in Methyl acetate
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Purity
99
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Solubility
10 mM in DMSO
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Storage Conditions
Solution, -20°C, protect from light, 2 years
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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4-Hydroxynonenal-d3 [CAS 148706-06-3]
4-Hydroxynonenal-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.