4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders[1][2][3][4][5][6].
CAS Number
[106-87-6]
Molecular Formula
C8H12O2
Molecular Weight
140.18
Smiles
C1(C2CCC3OC3C2)CO1
Target
Akt; Apoptosis; mTOR; PI3K; Reactive Oxygen Species (ROS)