5’-Azido-5’-deoxy-2’-O-methyluridine [CAS 194034-68-9]
5’-Azido-5’-deoxy-2’-O-methyluridine [CAS 194034-68-9]
SKU:QM-0071071
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Product Details
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Description
5’-Azido-5’-deoxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5’-Azido-5’-deoxy-2’-O-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[194034-68-9]
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Molecular Formula
C9H11N5O5
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Molecular Weight
269.21
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Smiles
O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1N=[N+]=[N-]
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Target
Nucleoside Antimetabolite/Analog
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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5’-Azido-5’-deoxy-2’-O-methyluridine [CAS 194034-68-9]
5’-Azido-5’-deoxy-2’-O-methyluridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.