5-CFDA-AM [CAS 124412-00-6]

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell[1].

[124412-00-6]

C28H20O11

532.45

O=C(C1=CC2=C(C3(C4=C(OC5=C3C=CC(OC(C)=O)=C5)C=C(OC(C)=O)C=C4)OC2=O)C=C1)OCOC(C)=O

Fluorescent Dye

99.81

DMSO : 125 mg/mL (ultrasonic)

-20°C (Powder, protect from light)

Blue Ice