5-CNAC [CAS 204852-67-5]

5-CNAC is an orally active enhancer of absorption, with no pharmacological activity on its own. 5-CNAC can significantly enhance the absorption efficiency of the drug (such as salmon calcitonin) when administered together with it in the gastrointestinal tract. 5-CNAC binds reversibly and non-covalently to peptide drugs, protecting them from degradation by gastrointestinal enzymes, increasing their lipid solubility, promoting passive transcellular absorption, and not damaging the integrity of the intestinal epithelium. 5-CNAC can be used in the research of adjuvants for orally administered peptide agents[1][2].

[204852-67-5]

C15H20ClNO4

313.78

O=C(O)CCCCCCCNC(C1=CC(Cl)=CC=C1O)=O

Others

99.49

4°C (Powder, stored under nitrogen)

Room Temperature