5’-DMTr-3’dA (Bz) -methylphosphonami dite

5’-DMTr-3’dA (Bz) -methylphosphonami dite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

C45H51N6O6P

802.9

CP(O[C@@H]1C[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N(C=N5)C6=C5C(NC(C7=CC=CC=C7)=O)=NC=N6)N(C(C)C)C(C)C

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature