5-Ethynyl-2'-deoxyuridine [CAS 61135-33-9]
5-Ethynyl-2'-deoxyuridine [CAS 61135-33-9]
SKU:QM-0075389-01
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Product Details
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Description
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation[1]. 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2]. 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[61135-33-9]
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Molecular Formula
C11H12N2O5
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Molecular Weight
252.23
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Smiles
O[C@H]1C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O[C@@H]1CO
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Target
PROTAC Linkers
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Isoform
Alkyl-Chain Linkers
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Purity
99.78
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Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H340, H361
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Precautions
H340, H361
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5-Ethynyl-2'-deoxyuridine [CAS 61135-33-9]
5-Ethynyl-2'-deoxyuridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.