5-Fluorouracil-13C,15N2 [CAS 1189423-58-2]
5-Fluorouracil-13C,15N2 [CAS 1189423-58-2]
SKU:QM-0074531
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Product Details
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Description
5-Fluorouracil-13C,15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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CAS Number
[1189423-58-2]
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Molecular Formula
C3 13CH3F 15N2O2
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Molecular Weight
133.06
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Smiles
O=C1C(F)=C[15NH][13C]([15NH]1)=O
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Target
Apoptosis; Endogenous Metabolite; HIV; Nucleoside Antimetabolite/Analog
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Purity
97
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Solubility
10 mM in DMSO|H2O : 16.67mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301
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Precautions
P264-P270-P330-P405-P501
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5-Fluorouracil-13C,15N2 [CAS 1189423-58-2]
5-Fluorouracil-13C,15N2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.