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5-LO/mPGES1-IN-1 [CAS 1492060-44-2]

5-LO/mPGES1-IN-1 [CAS 1492060-44-2]

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SKU:QM-0142070-01

£325.81 GBP
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  • Description

    5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO) . IC50 values are 0.3 and 0.4 μM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity[1].

  • CAS Number

    [1492060-44-2]

  • Molecular Formula

    C25H25ClN4O2S2

  • Molecular Weight

    513.07

  • Smiles

    O=C(C(CCCCCC)SC1=NC(Cl)=CC(NC2=NC(C3=CC4=C(C=CC=C4)C=C3)=CS2)=N1)O

  • Target

    Lipoxygenase; PGE synthase

  • Isoform

    5-LOX

  • Purity

    99

  • Solubility

    10 mM in DMSO

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

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Variant Variant total Quantity Price Variant total
1 mgQM-0142070-01
1 mgQM-0142070-01
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5 mgQM-0142070-02
5 mgQM-0142070-02
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5-LO/mPGES1-IN-1 [CAS 1492060-44-2]

5-LO/mPGES1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.