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SKU:QM-0142070-01
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5-LO/mPGES1-IN-1 (Compound 16) is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO) . IC50 values are 0.3 and 0.4 μM, respectively. 5-LO/mPGES1-IN-1 has anti-inflammatory activity[1].
[1492060-44-2]
C25H25ClN4O2S2
513.07
O=C(C(CCCCCC)SC1=NC(Cl)=CC(NC2=NC(C3=CC4=C(C=CC=C4)C=C3)=CS2)=N1)O
Lipoxygenase; PGE synthase
5-LOX
99
10 mM in DMSO
-20°C, 3 years (Powder)
Blue Ice
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5-LO/mPGES1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.