5-Methyluridine [CAS 1463-10-1]
5-Methyluridine [CAS 1463-10-1]
SKU:QM-0199626-01
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Product Details
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Description
5-Methyluridine (m5U) is an RNA modified nucleotide generated by RNA methyltransferases (such as TrmA and RumA), which mainly targets specific uracil sites in RNA molecules such as the T arm of tRNA and rRNA. 5-Methyluridine relies on enzyme recognition of RNA secondary/tertiary structures (such as the T loop of tRNA or the specific stem-loop structure of rRNA) and participates in physiological processes such as translation accuracy and ribosome function by stabilizing RNA folding or regulating base pairing[1][2][3].
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CAS Number
[1463-10-1]
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Molecular Formula
C10H14N2O6
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Molecular Weight
258.23
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Smiles
O[C@H]1[C@@H](O)[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1CO
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Target
Endogenous Metabolite
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Isoform
Human Endogenous Metabolite; Microbial Metabolite
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Concentration
10mM
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Purity
99.88
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Solubility
DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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5-Methyluridine [CAS 1463-10-1]
5-Methyluridine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.