β5i-IN-1

β5i-IN-1 is a potent and selective inhibitor of β5i with a IC50 of 8.463 nM. β5i-IN-1 releases TNF-α and IL-6 and influences the transcriptional activity of NF-κB. β5i-IN-1 can be used in study idiopathic pulmonary fibrosis[1].

C22H20BN3O4S2

465.35

O=C1N(CCSC)/C(S/C1=C\C2=CC=C(C3=CC=C(B(O)O)C=C3)O2)=N/C4=CC=CN=C4

Proteasome

10 mM in DMSO

Room temperature