6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene [CAS 1353042-00-8]
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene [CAS 1353042-00-8]
SKU:QM-0024079
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Product Details
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Description
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene (Compound 6) is a diterpenoid found in Premna obtusifolia. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene exhibits antibacterial against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin-resistant Enterococcus faecalis (VRE) (MIC = 37.5 μg/mL) . 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can significantly inhibit the release of the inflammatory mediator NO, with an IC50 value of 29.1 μM. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can be used for the researches of infection and inflammation[1].
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CAS Number
[1353042-00-8]
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Molecular Formula
C20H28O4
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Molecular Weight
332.43
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Smiles
OC1=C2[C@@]34[C@@](C(C)(CCC4)C)([H])[C@H]([C@@](OC3)([H])C2=CC(C(C)C)=C1O)O
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Target
Bacterial
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Shipping Conditions
Room temperature
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6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene [CAS 1353042-00-8]
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.