6-Diazo-5-oxo-L-nor-Leucine [CAS 157-03-9]
6-Diazo-5-oxo-L-nor-Leucine [CAS 157-03-9]
SKU:QM-0112995-01
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Product Details
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Description
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
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CAS Number
[157-03-9]
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Molecular Formula
C6H9N3O3
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Molecular Weight
171.15
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Smiles
N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O
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Target
Antibiotic; Bacterial; Glutaminase; Influenza Virus
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Purity
99.98
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Solubility
H2O : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H301+H311+H331
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Precautions
H301+H311+H331
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6-Diazo-5-oxo-L-nor-Leucine [CAS 157-03-9]
6-Diazo-5-oxo-L-nor-Leucine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.