6-Methoxypurine-9-β-D-5’ (R) -C-methylriboside

6-Methoxypurine-9-β-D-5’ (R) -C-methylriboside is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly (ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].

C12H16N4O5

296.28

O[C@]([H])(C)[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3OC)=C3N=C2)O1

Nucleoside Antimetabolite/Analog; Xanthine Oxidase

10 mM in DMSO

Room temperature