6-Raloxifene-β-D-glucopyranoside [CAS 334758-18-8]

6-Raloxifene-β-D-glucopyranoside, a derivative of Raloxifene, is a benzothiophene glucuronidated at the 6' postion. 6-Raloxifene-β-D-glucopyranoside is a selective and orally active estrogen receptor antagonist. 6-Raloxifene-β-D-glucopyranoside can be used for inhibiting bone loss and resorption, and lowering lipid levels. 6'-Raloxifene-β-D-glucopyranoside, compound Ia, is extracted from patent US5567820A[1].

[334758-18-8]

C34H37NO9S

635.72

O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC=C31)C5=CC=C(OCCN6CCCCC6)C=C5

Drug Metabolite; Estrogen Receptor/ERR

10 mM in DMSO

Room temperature