(6S) -CP-470711 [CAS 300552-09-4]

(6S) -CP-470711 (Compound 8) is an inhibitor for sorbitol dehydrogenase, that inhibits human and rat SDH with IC50 of 19 nM and 27 nM. (6S) -CP-470711 ameliorates the Streptozotocin -induced diabetes in rats models[1].

[300552-09-4]

C18H26N6O2

358.44

C[C@@H]1N(C2=NC([C@@H](O)C)=NC=C2)[C@@H](CN(C3=NC([C@H](O)C)=NC=C3)C1)C

Aldehyde Dehydrogenase (ALDH)

98.75

DMSO : 2 mg/mL (ultrasonic; warming; adjust pH to 6 with 1 M HCl; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature