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7ß,27-Dihydroxycholesterol [CAS 240129-43-5]

7ß,27-Dihydroxycholesterol [CAS 240129-43-5]

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SKU:QM-0063288

£685.45 GBP
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  • Description

    7ß,27-Dihydroxycholesterol (7β, 27-OHC) is a potent and selective activator of RORγt (Ki=120 nM) . 7ß,27-Dihydroxycholesterol promotes the differentiation of mouse and human CD4+ Th17 cells. 7ß,27-Dihydroxycholesterol also increases the production of IL-17 depended on CYP27A1[1].

  • CAS Number

    [240129-43-5]

  • Molecular Formula

    C27H46O3

  • Molecular Weight

    418.65

  • Smiles

    C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

  • Target

    ROR

  • Isoform

    RORγ

  • Purity

    99.5

  • Solubility

    10 mM in DMSO|Ethanol : ≥ 20mg/mL

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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7ß,27-Dihydroxycholesterol [CAS 240129-43-5]

7ß,27-Dihydroxycholesterol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.