7α,27-Dihydroxycholesterol [CAS 4725-24-0]
7α,27-Dihydroxycholesterol [CAS 4725-24-0]
SKU:QM-0091905
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Product Details
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Description
7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC) ; it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2) . Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC) .
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CAS Number
[4725-24-0]
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Molecular Formula
C27H46O3
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Molecular Weight
418.65
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Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@H]3O)C
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Target
EBI2/GPR183; Endogenous Metabolite
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Purity
99
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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7α,27-Dihydroxycholesterol [CAS 4725-24-0]
7α,27-Dihydroxycholesterol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.