7α-Hydroxy-DHEA [CAS 53-00-9]
7α-Hydroxy-DHEA [CAS 53-00-9]
SKU:QM-0104445-01
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Product Details
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Description
7α-Hydroxy-DHEA (7α-Hydroxydehydroepiandrosterone) is a 7α-hydroxylated metabolite of DHEA , catalyzed by intracellular steroid 7α-hydroxylases such as P450 2A1. 7α-Hydroxy-DHEA exhibits biological activity comparable to DHEA but does not convert into compounds with androgenic or estrogenic activity. It induces the activity of thermogenic enzymes such as mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme, enhancing heat production and reducing food utilization efficiency. As a more efficient and safer metabolite compared to DHEA, 7α-Hydroxy-DHEA holds potential for studies in the fields of obesity, metabolic diseases, and adrenal carcinoma[1].
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CAS Number
[53-00-9]
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Molecular Formula
C19H28O3
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Molecular Weight
304.42
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Smiles
C[C@@]12[C@]3([H])[C@]([C@@H](C=C1C[C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)(C(CC4)=O)C
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Target
Cytochrome P450; Mitochondrial Metabolism
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Shipping Conditions
Room temperature
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7α-Hydroxy-DHEA [CAS 53-00-9]
7α-Hydroxy-DHEA is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.