7-Hydroxycoumarinyl arachidonate [CAS 161180-11-6]
7-Hydroxycoumarinyl arachidonate [CAS 161180-11-6]
SKU:QM-0059215-01
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Product Details
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Description
7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer[1][2][3].
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CAS Number
[161180-11-6]
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Molecular Formula
C29H36O4
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Molecular Weight
448.59
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Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC1=CC=C2C=CC(OC2=C1)=O)=O
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Target
MAGL; Phospholipase
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Concentration
55.73 mM * 400 μL in Ethanol
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Purity
99.19
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Solubility
10 mM in DMSO
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Storage Conditions
Solution, -20°C, 2 years
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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7-Hydroxycoumarinyl arachidonate [CAS 161180-11-6]
7-Hydroxycoumarinyl arachidonate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.