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7-Hydroxymethotrexate [CAS 5939-37-7]
7-Hydroxymethotrexate [CAS 5939-37-7]
SKU:QM-0061479-01
£1,210.33 GBP
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Product Details
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Description
7-Hydroxymethotrexate is a major metabolite of Methotrexate. Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1][2].
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CAS Number
[5939-37-7]
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Molecular Formula
C20H22N8O6
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Molecular Weight
470.44
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Smiles
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3NC2=O)C)C=C1)=O
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Target
Drug Metabolite
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Purity
98.2
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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7-Hydroxymethotrexate [CAS 5939-37-7]
7-Hydroxymethotrexate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.