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7-Hydroxymethotrexate (sodium)
7-Hydroxymethotrexate (sodium)
SKU:QM-0005653
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Product Details
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Description
7-Hydroxymethotrexate sodium is a major metabolite of Methotrexate. Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis[1][2].
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Molecular Formula
C20H19N8Na3O6
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Molecular Weight
536.38
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Smiles
O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C(C=C1)=CC=C1N(C)CC2=NC(C(N)=NC(N)=N3)=C3N=C2O[Na])=O
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Target
Drug Metabolite
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Shipping Conditions
Room temperature
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7-Hydroxymethotrexate (sodium)
7-Hydroxymethotrexate (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.