7-Ketocholesterol [CAS 566-28-9]
7-Ketocholesterol [CAS 566-28-9]
SKU:QM-0076674-01
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Product Details
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Description
7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis (apoptosis) [1].
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CAS Number
[566-28-9]
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Molecular Formula
C27H44O2
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Molecular Weight
400.64
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Smiles
C[C@]1(CC2)[C@](CC[C@]1([H])[C@H](C)CCCC(C)C)([H])[C@@](C(C=C3C[C@H]4O)=O)([H])[C@@]2([H])[C@]3(CC4)C
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Target
Endogenous Metabolite; p38 MAPK
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Isoform
Human Endogenous Metabolite
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Purity
99.87
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Solubility
DMSO : 6.06 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, protect from light)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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7-Ketocholesterol [CAS 566-28-9]
7-Ketocholesterol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.