(7R) -SBP-0636457 [CAS 1422180-61-7]

(7R) -SBP-0636457 is the isomer of SBP-0636457 , and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers[1][2].

[1422180-61-7]

C25H36N4O4

456.58

O=C([C@H]1C(C)(C)C[C@](N21)([H])OCC[C@H](NC([C@@H](NC)C)=O)C2=O)N[C@@H]3CCCC4=C3C=CC=C4

IAP

98.36

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, stored under nitrogen)

Room Temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501