8-Br-7-CH-ADPR [CAS 1011457-95-6]
8-Br-7-CH-ADPR [CAS 1011457-95-6]
SKU:QM-0131239
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Product Details
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Description
8-Br-7-CH-ADPR (8-Bromo-7-deazaadenosine-5'-O-diphosphoribose) is a specific TRPM2 antagonist that inhibits TRPM2 activation by binding to the NUDT9 homology domain of the TRPM2 channel, thereby controlling the influx of cations through the cell membrane channel. 8-Br-7-CH-ADPR can be used to study the role of TRPM2 in pathological processes such as cell death, neurodegenerative diseases, myocardial infarction, and diabetes[1].
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CAS Number
[1011457-95-6]
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Molecular Formula
C16H23BrN4O14P2
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Molecular Weight
637.22
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Smiles
O[C@H]1[C@@H](O)[C@H](N(C(Br)=C2)C3=C2C(N)=NC=N3)O[C@@H]1COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)C(O)O4)(O)=O)(O)=O
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Target
TRP Channel
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Shipping Conditions
Room temperature
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8-Br-7-CH-ADPR [CAS 1011457-95-6]
8-Br-7-CH-ADPR is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.