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8-Br-ADPR [CAS 59259-77-7]

8-Br-ADPR [CAS 59259-77-7]

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SKU:QM-0082212

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  • Description

    8-Br-ADPR (8-Bromoadenosine-5'-O-diphosphoribose), an analogue of Adenosine 5′-diphosphoribose , is a TRPM2 modulator. 8-Br-ADPR is a human TRPM2 (hsTRPM2) inhibitor and a Nematostella vectensis (nvTRPM2) partial agonist (EC50 of 31.9 µM). 8-Br-ADPR regulates calcium release from the endoplasmic reticulum and sarcoplasmic reticulum[1].

  • CAS Number

    [59259-77-7]

  • Molecular Formula

    C15H22BrN5O14P2

  • Molecular Weight

    638.21

  • Smiles

    O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]4OC(O)[C@H](O)[C@@H]4O)(O)=O)(O)=O

  • Target

    TRP Channel

  • Shipping Conditions

    Room temperature

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8-Br-ADPR [CAS 59259-77-7]

8-Br-ADPR is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.