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8-Br-dGTP (sodium)

8-Br-dGTP (sodium)

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SKU:QM-0006061

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  • Description

    8-Br-dGTP (8-Bromo-dGTP) sodium (Compound 5), an 8-brominated purine nucleotide, is a syn-oriented analog of dGTP. 8-Br-dGTP sodium can be hydrolyzed by the enzyme hMTH1 protein. 8-Br-dGTP sodium inhibits dGTP-activated ADP reduction with a Ki of 56 μM. 8-Br-dGTP sodium has no significant genotoxicity and mutagenic potentials during DNA synthesis[1][2][3].

  • Molecular Formula

    C10H11BrN5Na4O13P3

  • Molecular Weight

    674

  • Smiles

    O[C@H]1C[C@H](N2C(Br)=NC3=C2NC(N)=NC3=O)O[C@@H]1COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O

  • Target

    Nucleoside Antimetabolite/Analog

  • Shipping Conditions

    Room temperature

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8-Br-dGTP (sodium)

8-Br-dGTP (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.