8-CPT-Cyclic AMP (sodium) [CAS 93882-12-3]
8-CPT-Cyclic AMP (sodium) [CAS 93882-12-3]
SKU:QM-0137184-01
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Product Details
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Description
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) . 8-CPT-Cyclic AMP sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC50Epac and is a potent Epac activator[1][2].
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CAS Number
[93882-12-3]
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Molecular Formula
C16H14ClN5NaO6PS
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Molecular Weight
493.79
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Smiles
NC1=NC=NC2=C1N=C(N2[C@@H]3O[C@@]4([H])[C@](OP(OC4)(O[Na])=O)([H])[C@H]3O)SC5=CC=C(Cl)C=C5
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Target
Phosphodiesterase (PDE) ; PKA
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Concentration
10mM
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Purity
99.91
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Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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8-CPT-Cyclic AMP (sodium) [CAS 93882-12-3]
8-CPT-Cyclic AMP (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.