8-pCPT-2′-O-Me-cAMP [CAS 510774-50-2]
8-pCPT-2′-O-Me-cAMP [CAS 510774-50-2]
SKU:QM-0088299
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Product Details
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Description
8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac) . 8-pCPT-2′-O-Me-cAMP activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM) . 8-pCPT-2′-O-Me-cAMP stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1][2][3].
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CAS Number
[510774-50-2]
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Molecular Formula
C17H17ClN5O6PS
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Molecular Weight
485.84
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Smiles
NC1=C2C(N([C@H]3[C@@H]([C@@]4([H])[C@](COP(O)(O4)=O)([H])O3)OC)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1
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Target
Ras
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Shipping Conditions
Room temperature
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8-pCPT-2′-O-Me-cAMP [CAS 510774-50-2]
8-pCPT-2′-O-Me-cAMP is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.