8-pCPT-2′-O-Me-cAMP (sodium) [CAS 634207-53-7]
8-pCPT-2′-O-Me-cAMP (sodium) [CAS 634207-53-7]
SKU:QM-0112582-01
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Product Details
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Description
8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac) . 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM) . 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1][2][3].
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CAS Number
[634207-53-7]
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Molecular Formula
C17H16ClN5NaO6PS
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Molecular Weight
507.82
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Smiles
NC1=C2C(N([C@H]3[C@@H]([C@@](O4)([H])[C@](COP4(O[Na])=O)([H])O3)OC)C(SC5=CC=C(Cl)C=C5)=N2)=NC=N1
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Target
Ras
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Purity
99.81
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Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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8-pCPT-2′-O-Me-cAMP (sodium) [CAS 634207-53-7]
8-pCPT-2′-O-Me-cAMP (sodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.