Δ8-Tetrahydrocannabinoquinone [CAS 19542-59-7]

Δ8-Tetrahydrocannabinoquinone (HU-336) is a potent antiangiogenic agent. Δ8-Tetrahydrocannabinoquinone inhibits angiogenesis by directly inducing apoptosis of vascular endothelial cells without changing the expression of pro- and antiangiogenic cytokines and receptors. Δ8-Tetrahydrocannabinoquinone is highly effective against tumor xenografts in nude mice[1].

[19542-59-7]

C21H28O3

328.45

O=C1C2=C(C(C(CCCCC)=C1)=O)OC(C)(C)[C@@]3([H])[C@@]2([H])CC(C)=CC3

Apoptosis

Room temperature