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SKU:QM-0141270-01
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A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM[1]. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner[2].
[1668553-26-1]
C46H55N7O7S
850.04
O=C(C(N1CCN2CCOCC2)=C(CCCOC3=C4C=CC=CC4=CC=C3)C5=C1C(C6=C(COC7=CC=C(N8CCN(S(=O)(N(C)C)=O)CC8)C=C7)N(C)N=C6C)=CC=C5)O
Apoptosis; Bcl-2 Family
Bcl-2; Bcl-W; Bfl-1; Mcl-1
99.86
DMSO : 10 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H320, H335
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A-1210477 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.