A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases[1].
CAS Number
[251992-66-2]
Molecular Formula
C15H12N2OS2
Molecular Weight
300.41
Smiles
O=C(C(S1)=CC2=C1C=NC=C2SC3=CC=C(C)C=C3)N
Target
Integrin
Concentration
10mM
Purity
98.96
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)