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A-446
A-446
SKU:QM-0067845
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Product Details
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Description
A-446, a chemical probe, is a potent glutaminase (GLS) inhibitor with an IC50 value of 31 nM[1].
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Molecular Formula
C20H20N6OS
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Molecular Weight
392.48
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Smiles
O=C(NC1=NN=C(S1)N2[C@H](C3)CN(C4=CC=CN=C4)[C@H]3C2)CC5=CC=CC=C5
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Target
Glutaminase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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A-446
A-446 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.