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A-446

A-446

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SKU:QM-0067845

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  • Description

    A-446, a chemical probe, is a potent glutaminase (GLS) inhibitor with an IC50 value of 31 nM[1].

  • Molecular Formula

    C20H20N6OS

  • Molecular Weight

    392.48

  • Smiles

    O=C(NC1=NN=C(S1)N2[C@H](C3)CN(C4=CC=CN=C4)[C@H]3C2)CC5=CC=CC=C5

  • Target

    Glutaminase

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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A-446

A-446 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.