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SKU:QM-0079829-01
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ABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activities[1].
[1042735-18-1]
C18H14N4OS
334.39
N#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1
CDK; GSK-3
CDK9; GSK-3α; GSK-3β
10mM
99.62
DMSO : 125 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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ABC1183 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.