Abemaciclib metabolite M18-d8
Abemaciclib metabolite M18-d8
SKU:QM-0141967-01
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Product Details
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Description
Abemaciclib metabolite M18-d8 is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1][2].
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Molecular Formula
C25H20D8F2N8O
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Molecular Weight
502.59
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Smiles
FC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5C([2H])([2H])C([2H])([2H])NC([2H])([2H])C5([2H])[2H]
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Target
CDK; Ligands for Target Protein for PROTAC
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Purity
99.87
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Solubility
DMSO : 32 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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Abemaciclib metabolite M18-d8
Abemaciclib metabolite M18-d8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.