ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4) . ABR-238901 has the potential for myocardial infarction (MI) research[1][2][3].
CAS Number
[1638200-22-2]
Molecular Formula
C11H9BrClN3O4S
Molecular Weight
394.63
Smiles
O=S(NC1=C(O)C(Cl)=CN=C1)(C2=CN=C(C(Br)=C2)OC)=O
Target
Toll-like Receptor (TLR)
Purity
98.92
Solubility
DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)