Ac-RGDS-NH2 [CAS 122207-62-9]

Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis[1].

[122207-62-9]

C17H30N8O8

474.47

NC([C@H](CO)NC([C@H](CC(O)=O)NC(CNC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)=O

Integrin

Room temperature