AC2 selective-IN-1

AC2 selective-IN-1 (compound 14) is a potent (IC50=4.45 μM), non-toxic, and selective mAC2 inhibitor[1].

C41H47N8O8P

810.83

NC1=C2C(N(CCOCP(N[C@H](C(OC(C)C)=O)CC3=CC=CC=C3)(N[C@@H](CC4=CC=CC=C4)C(OC(C)C)=O)=O)C=C2C5=CC=CC(C(N6)=NOC6=O)=C5)=NC=N1

Adenylate Cyclase

10 mM in DMSO

Room temperature