Acetylene-linker-Val-Cit-PABC-MMAE [CAS 1411977-95-1]
Acetylene-linker-Val-Cit-PABC-MMAE [CAS 1411977-95-1]
SKU:QM-0155554-01
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Product Details
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Description
Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) consists the ADCs linker (Acetylene-linker-Val-Cit-PABC) and potent tubulin inhibitor (MMAE) . Acetylene-linker-Val-Cit-PABC-MMAE (LCB14-0602) is a agent-linker conjugate for ADC. Acetylene-linker-Val-Cit-PABC-MMAE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[1411977-95-1]
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Molecular Formula
C67H106N10O16
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Molecular Weight
1307.62
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Smiles
O=C([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(COCCOCCOCC#C)=O)=O)NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)CCC2)=O)OC)[C@@H](C)CC)C)=O)=O)=O)C=C1
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Target
Drug-Linker Conjugates for ADC
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Isoform
Auristatin
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Purity
95.21
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, stored under nitrogen)
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Shipping Conditions
Room Temperature
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Acetylene-linker-Val-Cit-PABC-MMAE [CAS 1411977-95-1]
Acetylene-linker-Val-Cit-PABC-MMAE is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.