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AChE/BACE1/GSK3β-IN-1 [CAS 2866066-81-9]
AChE/BACE1/GSK3β-IN-1 [CAS 2866066-81-9]
SKU:QM-0069267
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Product Details
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Description
AChE/BACE1/GSK3β-IN-1 is an orally active triple inhibitor of AChE/BACE1/GSK3β. AChE/BACE1/GSK3β-IN-1 has effective inhibitory activity against AChE, BACE1 and GSK3β with IC50 values of 1.0 μM, 20 μM and 15 μM, respectively. AChE/BACE1/GSK3β-IN-1 has good blood-brain barrier penetrability, suitable bioavailability. AChE/BACE1/GSK3β-IN-1 can be used for the research of Alzheimer's disease (AD) [1].
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CAS Number
[2866066-81-9]
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Molecular Formula
C26H27FN2O4
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Molecular Weight
450.5
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Smiles
O=C1C=CC2=C(OCCCN3CCC(NCC4=CC(F)=CC=C4)CC3)C5=C(OC=C5)C=C2O1
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Target
Beta-secretase; Cholinesterase (ChE) ; GSK-3
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Isoform
AChE; BACE1; GSK-3β
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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AChE/BACE1/GSK3β-IN-1 [CAS 2866066-81-9]
AChE/BACE1/GSK3β-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.