AChE-IN-39

AChE-IN-39 (Compound 7c) is an AChE inhibitor (IC50: 0.058 μM) . AChE-IN-39 has DPPH scavenging activity. AChE-IN-39 improves the cognitive impairment in AlCl3-induced amnesia animal model. AChE-IN-39 can be used for research of Alzheimer's disease[1].

C19H15NO3

305.33

O=C(C1=CC2=C(C=CC=C2)O1)/C=C/NC3=CC(C(C)=O)=CC=C3

Cholinesterase (ChE)

10 mM in DMSO

Room temperature