AChE-IN-67

AChE-IN-67 (compound 8n) is a potent AChE inhibitor, with an IC50 of 0.033 μM. AChE-IN-67 exhibits activity similar to Donepezil. AChE-IN-67 exhibits high blood-brain barrier (BBB) permeability. AChE-IN-67 can be used for Alzheimer's disease research[1].

C16H15N5O3

325.32

O=C(N/N=C/C1=CC=CN1)CN(N(C)C(C2=C3C=CC=C2)=O)C3=O

Cholinesterase (ChE)

AChE; BChE

Room temperature