Acremorin E

Acremorin E (Compound 7) is a terpenoid compound with antifungal activity. Acremorin E exerts its anti-C. gattiii effect by upregulating genes related to biosynthesis and RNA binding of ribosomes, as well as inhibiting RNA and nucleic acid metabolism and ATPase activity (MIC: 8 μg/mL) [1].

C23H31ClO5

422.94

CC1=C(C(O)=C(C(O)=C1Cl)C/C=C([C@H](C[C@]2([C@@H](CCC([C@@H]2C)=O)C)C)O)\C)C=O

Fungal

Room temperature