Adefovir diphosphate [CAS 129556-87-2]

Adefovir diphosphate is an antiviral compound with activity against hepatitis B virus (HBV) . Adefovir diphosphate blocks the replication of HBV by inhibiting reverse transcriptase. Adefovir diphosphate has also shown activity against other viruses such as herpes viruses and human immunodeficiency virus. Adefovir diphosphate is used as an effective inhibitory option in the suppression of chronic hepatitis B. The mechanism of action of Adefovir diphosphate involves blocking the autophosphorylation of growth factor receptors, thereby potentially reducing the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B[1].

[129556-87-2]

C8H13N5O7P2

353.17

O=P(O)(OP(O)(COCCN1C=NC2=C1N=CN=C2N)=O)O

Endogenous Metabolite

Room temperature