Adenosine 3'-phosphate 5'-phosphosulfate (lithium, hydrate)
Adenosine 3'-phosphate 5'-phosphosulfate (lithium, hydrate)
SKU:QM-0110603
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Product Details
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Description
Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group[1][2][3].
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Molecular Formula
C10H15N5O13P2S.xLi.yH2O
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Smiles
O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(NP(O)(O)=O)=C3N=C2)O[C@@H]1COP(OS(=O)(O)=O)(O)=O.[Li].[x].O.[y]
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Target
P2Y Receptor
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Isoform
P2Y1 Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Adenosine 3'-phosphate 5'-phosphosulfate (lithium, hydrate)
Adenosine 3'-phosphate 5'-phosphosulfate (lithium, hydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.