Aderbasib-d3

Aderbasib-d3 (INCB007839-d3) is deuterium labeled Aderbasib. Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2+?breast cancer, gliomas, et al[1].

C21H25D3N4O5

419.49

O=C(N([C@@H]1C(N2CCN(CC2)C3=CC=CC=C3)=O)CC4(C[C@@H]1C(NO)=O)CC4)OC([2H])([2H])[2H]

Isotope-Labeled Compounds; MMP

Room temperature