(+) -Adomeglivant [CAS 872260-19-0]

(+) -Adomeglivant ((+) -LY2409021) is a potent and selective glycogenotropin receptor antagonist with glucose-lowering activity. (+) -Adomeglivant reduces fasting blood glucose levels in both healthy subjects and patients with type 2 diabetes. The use of (+) -Adomeglivant can help investigate the mechanisms of hyperglycemia in type 2 diabetes. The antagonistic effect of (+) -Adomeglivant makes it challenging to assess the metabolic consequences of postprandial hyperglycemia[1].

[872260-19-0]

C32H36F3NO4

555.63

O=C(O)CCNC(C1=CC=C([C@H](OC2=CC(C)=C(C3=CC=C(C(C)(C)C)C=C3)C(C)=C2)CCC(F)(F)F)C=C1)=O

Endogenous Metabolite

Room temperature