ADS1017

ADS1017 is the antagonist for histamine receptor and muscarinic receptor, that exhibits good affinities to hH3R, hH4R, hM2R and hM4R with pKi of 6.8, 5.5, 7.4 and 7.2. ADS1017 exhibits analgesic and anti-allodynic efficacy in mice Capsaicin -or Oxaliplatin (HY-17371) -induced pain models[1].

C29H45N5O

479.7

NC(N(CCCCN1CCN(CCCCCCCOC2=CC=CC=C2)CC1)CC3=CC=CC=C3)=N

Histamine Receptor; mAChR

Room temperature