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AES-350 [CAS 847249-57-4]

AES-350 [CAS 847249-57-4]

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QM-0146464-01

£450.95 GBP
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Product Details

  • Description

    AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research[1].

  • CAS Number

    [847249-57-4]

  • Molecular Formula

    C18H20N2O3

  • Molecular Weight

    312.36

  • Smiles

    O=C(NO)C1=CC=C(NC(C2=CC=C(C(C)(C)C)C=C2)=O)C=C1

  • Target

    Apoptosis; HDAC

  • Isoform

    HDAC11; HDAC3; HDAC6

  • Purity

    99.3

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H228, H315, H319

  • Precautions

    H228, H315, H319
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Variant Variant total Quantity Price Variant total
5 mgQM-0146464-01
5 mgQM-0146464-01
£450.95/ea		 £0.00
£450.95/ea £0.00
10 mM - 1 mLQM-0146464-02
10 mM - 1 mLQM-0146464-02
£489.83/ea		 £0.00
£489.83/ea £0.00
10 mgQM-0146464-03
10 mgQM-0146464-03
£625.91/ea		 £0.00
£625.91/ea £0.00
25 mgQM-0146464-04
25 mgQM-0146464-04
£1,087.61/ea		 £0.00
£1,087.61/ea £0.00
50 mgQM-0146464-05
50 mgQM-0146464-05
£1,503.14/ea		 £0.00
£1,503.14/ea £0.00
100 mgQM-0146464-06
100 mgQM-0146464-06
£2,086.34/ea		 £0.00
£2,086.34/ea £0.00
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AES-350 [CAS 847249-57-4]

AES-350 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.